Sculptra® Aesthetic: For smile lines and marionette lines

Youthful skin starts within

Sculptra® Aesthetic works subtly and gradually over time for a more youthful-looking appearance. Unlike hyaluronic acid (HA) fillers, Sculptra Aesthetic helps stimulate your skin’s own natural collagen production to help restore its inner structure and increase facial volume that has been lost to aging.1-3 Sculptra Aesthetic is intended for use in people with healthy immune systems as a one-time treatment regimen of up to four injection sessions that are scheduled about three weeks apart.


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Smile lines

80% of patients were still satisfied with their treatment results 25 months after their last injection.5*

*Clinical study ended at 25 months.
Before Sculptra® Aesthetic treatment After Sculptra® Aesthetic treatment

Before and after

The results speak for themselves. Look through our gallery to see how Sculptra Aesthetic subtly delivers a more youthful-looking appearance over a series of treatments.


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Franca

Age 42
Real Sculptra Aesthetic patient

25 months after first treatment. Individual results may vary.

Collagen by the numbers

Collagen is a key structural component of smooth, healthy-looking skin. As you age, your body’s collagen production decreases. In fact, you lose about 1% of collagen per year after the age of 20.6 This is when you may start to notice the formation of wrinkles. Luckily, Sculptra Aesthetic can help, even if decades of collagen loss have already occurred.

You lose about 1% of collagen per year after the age of 20.6

Learn how it works »
Marionette lines

87% of RealSelf users say it’s “worth it.”7

Read about treatment value »

References:
  1. Stein P, Vitavska O, Kind P, Hoppe W, Wieczorek H, Schürer NY. The biological basis for poly-L-lactic acid-induced augmentation. J Dermatol Sci . 2015;78(1):26–33.
  2. Goldberg D, Guana A, Volk A, Daro-Kaftan E. Single-arm study for the characterization of human tissue response to injectable poly-L-lactic acid. Dermatol Surg. 2013;39(6):915–922.
  3. Sculptra Aesthetic injectable poly-L-lactic acid. Instructions for Use. Galderma Laboratories. September 2014.
  4. Narins RS, Baumann L, Brandt FS, et al. A randomized study of the efficacy and safety of injectable poly-L-lactic acid versus human-based collagen implant in the treatment of nasolabial fold wrinkles. J Am Acad Dermatol. 2010;62(3);448–462.
  5. Brown SA, Rohrich RJ, Baumann L, et al. Subject global evaluation and subject satisfaction using injectable poly-L-lactic acid versus human collagen for the correction of nasolabial fold wrinkles. Plast Reconstr Surg. 2011;127(4):1684–1692.
  6. Obagi S. Why does skin wrinkle with age? What is the best way to slow or prevent this process? Scientific American Web site. http://www.scientificamerican.com/article/why-does-skin-wrinkle-wit/. Published September 26, 2005. Accessed January 27, 2013.
  7. Reviews from the Community. RealSelf website. https://www.realself.com/Sculptra/reviews. Accessed March 7, 2016.

Important Safety Information

Indication: Sculptra® Aesthetic (injectable poly-L-lactic acid) is indicated for use in people with healthy immune systems as a single regimen for the correction of shallow to deep nasolabial fold contour deficiencies and other facial wrinkles in which deep dermal grid pattern (cross-hatch) injection technique is appropriate.

Sculptra Aesthetic should not be used by people that are allergic to any ingredient of the product or have a history of keloid formation or hypertrophic scarring. Safety has not been established in patients who are pregnant, lactating, breastfeeding, or under 18 years of age.

Sculptra Aesthetic has unique injection requirements and should only be used by a trained physician. Contour deficiencies should not be overcorrected because they are expected to gradually improve after treatment.

Sculptra Aesthetic should not be injected into the blood vessels as it may cause vascular occlusion, infarction or embolic phenomena. Use at the site of skin sores, cysts, pimples, rashes, hives or infection should be postponed until healing is complete. Sculptra Aesthetic should not be injected into the red area (vermillion) of the lip or in the peri-orbital area.

The most common side effects after initial treatment include injection site swelling, tenderness, redness, pain, bruising, bleeding, itching and lumps. Other side effects may include small lumps under the skin that are sometimes noticeable when pressing on the treated area. Larger lumps, some with delayed onset with or without inflammation or skin discoloration, have also been reported.

Sculptra Aesthetic is available only through a licensed practitioner. View the complete Instructions for Use.

Important Safety Information | Instructions for Use

Indication: Sculptra® Aesthetic (injectable poly-L-lactic acid) is indicated for use in people with healthy immune systems as a single regimen for the correction of shallow to deep nasolabial fold contour deficiencies and other facial wrinkles in which deep dermal grid pattern (cross-hatch) injection technique is appropriate.